CAS number: 125-71-3
Therapeutic segment: Antitussive (Cough Suppressant)
API class/drug class: Centrally acting NMDA receptor antagonist; Sigma-1 receptor agonist
Chemical name: (1S,9S,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Molecular formula: C18H25NO
Molecular weight: 271.4 g/mol
Form: White to slightly yellow crystalline powder
Packaging type: Double LDPE bags packed in HDPE drums or equivalent pharma-grade, moisture-protective packaging
Storage conditions: Store at 20°C to 25°C (68°F to 77°F). Protect from light and moisture
Specification: As per USP/PhEur/IP (as applicable) or in-house specifications
Application area: Temporary relief of non-productive (dry) cough caused by minor throat and bronchial irritation
GMP: Y
DMF: Y
USFDA: Y

EDQM: -

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Product Description:

Dextromethorphan is a centrally acting antitussive API classified as an NMDA receptor antagonist and sigma-1 receptor agonist. Supplied as a white to slightly yellow crystalline powder, it modulates the cough reflex through central nervous system pathways. The API is widely incorporated into oral solid and liquid pharmaceutical formulations intended for dry cough management. It is packaged in pharma-grade, moisture-protective containers to ensure stability under recommended storage conditions.

As a leading distribution partner, Molkem Chemicals ensures reliable supply of products aligned with industry quality standards and regulatory expectations. Each product is delivered as per agreed specifications, supported by standard documentation including COA, SDS, and TDS. If required, our technical team can provide additional stability data and regulatory assistance.

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