CAS number: 42399-41-7
Therapeutic segment: Cardiovascular (Antihypertensive / Antianginal)
API class/drug class: Calcium channel blocker (Benzothiazepine class)
Chemical name: [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Molecular formula: C22H26N2O4S
Molecular weight: 414.5 g/mol
Form: White to off-white crystalline powder
Packaging type: Double LDPE bags packed in HDPE drums or equivalent pharma-grade, moisture-protective packaging
Storage conditions: Store in a cool, dry place; protect from light and moisture
Specification: As per USP/PhEur/IP (as applicable) or in-house specifications
Application area: Treatment of hypertension, chronic stable angina, and variant (Prinzmetal’s) angina; also used in the management of atrial fibrillation/flutter and paroxysmal supraventricular tachycardia (PSVT)
GMP: Y
DMF: Y
USFDA: -
EDQM: Y

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Product Description:

Diltiazem is a benzothiazepine-class calcium channel blocker API supplied as a white to off-white crystalline powder for use in cardiovascular pharmaceutical formulations. It inhibits calcium ion influx into cardiac and vascular smooth muscle cells, thereby modulating vascular tone and cardiac conduction. It is incorporated into oral dosage forms intended for the management of hypertension, angina, and certain supraventricular arrhythmias. It is packaged in moisture-protective, pharma-grade containers to ensure stability under recommended storage conditions.

As a leading distribution partner, Molkem Chemicals ensures reliable supply of products aligned with industry quality standards and regulatory expectations. Each product is delivered as per agreed specifications, supported by standard documentation including COA, SDS, and TDS. If required, our technical team can provide additional stability data and regulatory assistance.

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